RSS Bandit is a powerful open source feed reader. Features searches within your feeds, search folders, easy feed detection, excellent synchronization, special folders, and much more. RSS Bandit developers are actually listening to their users and the road map is full of powerful goodies. [Requires: .Net] [Platform: Windows]
Omea Reader is an easy to use, all-in-one RSS reader, NNTP news reader, and web bookmark manager. It's fast, it aggregates, you can organize your information with it, and what really makes it unique are the additional features: lightning-fast searches, flexible filing, contextual access, and extensibility. Comes from the company that develops IntelliJ IDEA, a highly praised advanced Java IDE. [Requires: .Net] [Platform: Windows]
NewzCrawler is a reader which supports various formats apart from RSS, so it can, for example, monitor web pages which don't provide RSS feeds. Also supports NNTP (Usenet groups) and includes fully functional WYSIWYG weblog client allowing news posting on XML-RPC servers such as Blogger, MetaWeblog, MovableType and LiveJournal. Features search channels, the CommentAPI protocol and can use both Gecko and IE browsers for rendering pages. [Price: $25.00] [Platform: Windows]
GreatNews "The Intelligent RSS Reader" is an excellent fast reader which features flexible labeling, search channels, synchronization via Bloglines and a clean and usable interface.
PulpFiction is a next-generation, easy-to-use, powerful RSS/Atom feed reader. Featuring a familiar Mail-like interface, PulpFiction will fetch, organize, and display news and articles from thousands of weblogs and websites. Leveraging Mail's familiar interface and ease of use, PulpFiction throws some serious muscle behind your news reading. Powerful, flexible filters move, mark, and process articles. Flags, sounds, and dock icons alert you to new or important posts. AppleScript support allows you to extend PulpFiction to work with your entire digital hub: Mail, Safari, the Finder, and more. [Price: $25, Free lite version also available] [Platform: Mac OS X]
NetNewsWire is an easy-to-use RSS and Atom newsreader for Mac OS X. Its familiar three-paned interface—similar to Apple Mail—can fetch and display news from thousands of different websites and weblogs. There is also a free lite version of NetNewsWire, that doesn't include some of the advanced features of the commercial version. [Price: $24.95, Free lite version also available] [Platform: Mac OS X]
RSSOwl lets you gather, organize, update, and store information from any compliant source in a convenient, easy to use interface, save selected information in various formats for offline viewing and sharing, and much more. It's easy to configure, available in many many languages and the best of all: It's platform-independent. [Platform: Java (Cross Platform)]
BloxOr is a new, very nice and fast online feed aggregator with a look and feel of a desktop app. BloxOr uses the XML User Interface Language (XUL) so it will work only in Gecko browsers like Mozilla or Firefox. [Platform: Web]